Q4 2025 Cytek BioSciences Inc Earnings Call

February 26, 2026

Operator: Thank you for standing by. My name is Tina. I will be your conference operator today. At this time, I would like to welcome everyone to the Cytek Biosciences Q4 2025 Earnings Call. All lines have been placed on mute to prevent any background noise. After the speaker's remarks, there will be a question and answer session. To ask a question, simply press star one on your telephone keypad. To withdraw your question, press star one again. It is now my pleasure to turn the call over to Paul Goodson, Head of Investor Relations. You may begin.

Speaker #1: Thank you for standing by. My name is Tina, and I will be your conference operator today. At this time, I would like to welcome everyone to the Cytek Sciences fourth-quarter 2025 earnings call.

Speaker #1: All lines have been placed on mute to prevent any background noise. After the speaker's remarks, there will be a question-and-answer session. To ask a question, simply press star 1 on your telephone keypad.

Speaker #1: To withdraw your question, press star 1 again. It is now my pleasure to turn the call over to Paul Goodson, Head of Investor Relations, you may begin.

Speaker #2: Thank you, Operator. Earlier today, Cytek Biosciences released financial results for the fourth quarter and year-ended December 31st, 2025. If you haven't received this news release or you'd like to be added to the company's distribution list, please send an email to investors@cytekbio.com.

Paul Goodson: Thank you, operator. Earlier today, Cytek Biosciences released financial results for the Q4 and year ended 31 December 2025. If you haven't received this news release or you'd like to be added to the company's distribution list, please send an email to investors@cytekbio.com. A copy of the news release is also available on the investor relations section of Cytek's website at investors.cytekbio.com. Joining me today from Cytek are Wenbin Jiang, CEO, and Bill McCombe, CFO. Please note that we will be referencing a slide presentation during the call today that has been posted to the investor section of our corporate website. As a reminder, on slide 2, we will make statements during this call that are forward-looking statements within the meaning of the federal securities laws, including statements regarding Cytek's business plans, strategies, opportunities, and financial projections.

Speaker #2: A copy of the news release is also available on the Investor Relations section of Cytek's website at investors.cytekbio.com. Joining me today from Cytek are Wenbin Jiang, CEO, and Bill McCombe, CFO.

Speaker #2: Please note that we will be referencing a slide presentation during the call today that has been posted to the Investor section of our corporate website.

Speaker #2: As a reminder, on slide 2, we will make statements during this call that are forward-looking statements within the meaning of the Federal Securities Laws, including statements regarding Cytek's business plans, strategies, opportunities, and financial projections.

Speaker #2: These statements are based on the company's current expectations and inherently involve significant risks and uncertainties that could cause actual results or events to materially differ from those anticipated in these statements.

Paul Goodson: These statements are based on the company's current expectations and inherently involve significant risks and uncertainties that could cause actual results or events to materially differ from those anticipated in these statements. Additional information regarding these risks and uncertainties appears in our slide presentation in the section entitled Forward-Looking Statements in the press release Cytek issued today and in Cytek's filings with the SEC. This call will also include a discussion of certain financial measures that are not calculated in accordance with generally accepted accounting principles. Additional information regarding our use of non-GAAP financial measures, including reconciliations to the most directly comparable GAAP financial measures, may be found on our slide presentation and in today's press release.

Speaker #2: Additional information regarding these risks and uncertainties appears in our slide presentation, in the section entitled "Forward-Looking Statements in the Press Release Cytek Issued Today and in Cytek's filings with the SEC." This call will also include a discussion of certain financial measures that are not calculated in accordance with generally accepted accounting principles.

Speaker #2: Additional information regarding our use of non-GAAP financial measures including reconciliations to the most directly comparable GAAP financial measures may be found on our slide presentation and in today's press release.

Speaker #2: While the company believes these non-GAAP financial measures provide useful information for investors, the presentation of this information is not intended to be considered in isolation or as a substitute for the financial information presented in accordance with GAAP.

Paul Goodson: While the company believes these non-GAAP financial measures provide useful information for investors, the presentation of this information is not intended to be considered in isolation or as a substitute for the financial information presented in accordance with GAAP. Except as required by law, Cytek disclaims any duty to update any forward-looking statements, whether because of new information, future events, or changes in its expectations. This conference call contains time-sensitive information and is accurate only as of the live broadcast, 26 February 2026. With that, I will turn the call over to Wenbin.

Speaker #2: Except as required by law, Cytek disclaims any duty to update any forward-looking statements, whether because of new information, future events, or changes in its expectations.

Speaker #2: This conference call contains time-sensitive information and is accurate only as of the live broadcast February 26th, 2026. With that, I will turn the call over to Wenbin.

Speaker #3: Thanks, Paul. Welcome, everyone, and thank you for your interest in Cytek. On today's call, I would like to start with a discussion on our performance in the fourth quarter and the full year 2025, before turning the call over to Bill for a detailed look at our financials and our outlook.

Wenbin Jiang: Thanks, Paul. Welcome, everyone, and thank you for your interest in Cytek. On today's call, I would like to start with a discussion on our performance in Q4 and the full year 2025 before turning the call over to Bill for a detailed look at our financials and our outlook. Turning to slide 3. We ended 2025 in line with our expectations and delivered accelerating revenue growth quarter-over-quarter throughout the year, despite challenging industry conditions. Q4 revenue in 2025 reached $62.1 million, representing a year-over-year increase of 8% compared to the same period in 2024, and notably, the highest revenue historically achieved in a quarter at Cytek.

Speaker #3: Turning to slide 3, we exited 2025 in line with our expectations and delivered accelerating revenue growth quarter over quarter throughout the year. Despite challenging industry conditions, fourth-quarter revenue in 2025 reached $62.1 million, representing a year-over-year increase of 8% compared to the same period in 2024, and notably the highest revenue historically achieved in a quarter at Cytek.

Speaker #3: This growth was driven by a continuation of the trend we saw in the third quarter—namely, stabilization and growth in the US, a turnaround in the EU, continued strength in APAC, and a solid expansion of our recurring revenue businesses worldwide.

Wenbin Jiang: This growth was driven by a continuation of the trend we saw in Q3, namely stabilization and growth in the US, a turnaround in the EU, continued strength in APAC, and the solid expansion of our recurring revenue businesses worldwide. Turning to slide 4. Geographically, in Q4, EMEA and APAC both posted double-digit year-over-year percentage revenue growth increases, with solid gains across instruments, reagents, and service. Year-over-year Q4 revenue growth in EMEA was driven by strong instrument demand from academic and government customers and continued momentum in service revenue, partially offset by a decline in instrument revenue from biotech, pharma, and CRO customers.

Speaker #3: Turning to slide 4, geographically in the fourth quarter, Amir and APAC both posted double-digit year-over-year percentage revenue increases. With solid gains across instruments, divisions, and service, year-over-year fourth-quarter revenue growth in Amir was driven by strong instrument demand from academic and government customers.

Speaker #3: And continued momentum in service revenue. Partially offset by a decline in instrument revenue from BioNTech, pharma, and CRO customers. For the fourth quarter of 2025 in the US, we saw mid-single-digit year-over-year growth in total revenue.

Wenbin Jiang: For the Q4 of 2025 in the US, we saw mid-single-digit year-over-year growth in total revenue, driven by sentiment shifting in the academic and government market. This increase was partially offset by a decline in instrument sales to the biotech pharma and CRO market, reflecting the typical fluctuations we see with this sector, particularly after a strong Q3. Turning to slide 5. Full year revenue in 2025 reached $201.5 million, representing a year-over-year increase of 1% compared to 2024. I want to take a moment to highlight the improvement in our revenue growth during 2025. For the first half of the year, total revenue was down almost 5% year-over-year due to public policy issues affecting life sciences spending.

Speaker #3: Driven by sentiment shifting in the academic and government markets, this increase was partially offset by a decline in instrument sales to the BioNTech, pharma, and CRO markets, reflecting the typical fluctuations we see with this sector, particularly after a strong third quarter.

Speaker #3: Turning to slide 5, full-year revenue in 2025 reached $201.5 million. Representing a year-over-year increase of 1% compared to 2024. I want to take a moment to highlight the improvement in our revenue growth during 2025.

Speaker #3: For the first half of the year, total revenue was down almost 5% year-over-year due to public policy issues affecting life sciences spending. Our momentum pivoted in the second half, with total revenue up 5% compared to the second half in 2024.

Wenbin Jiang: Our momentum pivoted in the second half, with total revenue up 5% compared to the second half in 2024. This return to growth reflects improved trends and increased customer demand. Importantly, our overall performance in 2025 demonstrates the durability of our business, particularly when compared to the evidence of decline in cell analysis and life science instrument demand through the end of Q3. We believe our success at delivering revenue growth in 2025 was achieved through the strength of our brand and technology, the diversification of our revenue streams across multiple geographic regions, and a growing contribution from recurring revenue. We believe this return to growth will continue in 2026.

Speaker #3: This return to growth reflects improved trends and increased customer demand. Importantly, our overall performance in 2025 demonstrates the durability of our business. Particularly, when compared to the evidence of declines in share analysis and life science instrument demand, through the end of the third quarter.

Speaker #3: We believe our success at delivering revenue growth in 2025 was achieved through the strength of our brand and technology. The diversification of our revenue streams across multiple geographic regions, and a growing contribution from recurring revenue.

Speaker #3: We believe this return to growth will continue in 2026. I would now like to update you on the progress our team has made across our core strategic pillars: instruments, applications, bioinformatics, and clinicals to further reinforce Cytek's position as a market leader in next-gen share analysis solutions.

Wenbin Jiang: I would now like to update you on the progress our team has made across our core strategic pillars, instruments, applications, bioinformatics, and clinical, to further reinforce Cytek's position as a market leader in next-gen cell analysis solutions. Starting with our core instrument on slide 6. In Q4, we expanded our global footprint by 208 instruments, bringing Cytek's total installed base to 3,664 units. In 2025's challenging market environment, we believe the growth in our FFPE instrument revenue reflects the superior performance of Cytek's products, our brand recognition, and the underlying strength of our core business. We are particularly pleased with the growth in our cell sorter unit volume, which grew 22% in 2025 compared to the prior year and accelerated to 26% growth in Q4 over the prior year period.

Speaker #3: Starting with our core instruments, on slide 6, in the fourth quarter, we extended our global footprint by 208 instruments, bringing Cytek's total installed base to 3,664 units.

Speaker #3: In 2025, the challenging market environment, we believe the growth in our FSC instrument revenue reflects the superior performance of Cytek's products. Our brand recognition and the underlying strength of our core business.

Speaker #3: We are particularly pleased with the growth in our sales for the unit volume, which grew 22% in 2025 compared to the prior year, and accelerated to 26% growth in the fourth quarter over the prior year period.

Speaker #3: We have also been very pleased with the performance of our new Cytek Aurora Evo system. In the short time since its launch last May, it has been tremendously successful, driving 21% unit growth in the combined Aurora category in the fourth quarter versus Q4 of 2024.

Wenbin Jiang: We have also been very pleased with the performance of our new Cytek Aurora Evo system. In the short time since its launch last May, it has been tremendously successful, driving 21% unit growth in the combined Aurora category in the Q4 versus Q4 of 2024. I'm also pleased to highlight that the Muse Micro system was recently awarded the 2025 BioTech Breakthrough Award for the Drug Discovery Solution of the Year. As we previously noted, the Muse Micro analyzer is an ideal choice for researchers and labs seeking cost-effective flow cytometry solutions and has had a very strong reception since its introduction last year. These new product offerings reflect our commitment to maintaining our position at the forefront of the technology innovation in cell analysis generally, and flow cytometry specifically.

Speaker #3: I'm also pleased to highlight that the new micro system was recently awarded the 2025 BioNTech Breakthrough Award for the just discovery solution of the year.

Speaker #3: As we previously noted, the new micro analyzer is an ideal choice for researchers and labs seeking cost-effective flow cytometry solutions, and has had a very strong acceptation since its introduction last year.

Speaker #3: These new product offerings reflect our commitment to maintaining our position as the fourth brand of the technology innovation in cell analysis generally and flow cytometry specifically.

Speaker #3: I would now like to turn to our next growth pillar applications. Which is comprised of our liaison business. We delivered more than 20% growth in liaisons in the fourth quarter in all of our geographic regions except the US.

Wenbin Jiang: I would now like to turn to our next growth pillar, applications, which is comprised of our reagent business. We delivered more than 20% growth in reagents in the Q4 in all of our geographic regions except the US. Our reagent growth continues to be driven by the improvements we put in place in 2025, including best-in-class delivery times, a large catalog of reagents, and new initiatives and strategies on reagent sales. Turning to slide 7. Our recurring revenue continues to strengthen as our installed instrument base expands. For all of 2025, recurring revenue represented 34% of total revenue and notably grew 21% year-over-year. We expect the recurring revenue proportion of total revenue will continue to grow steadily with increased cumulative instrument placements and to become an increasingly larger share of our business over time.

Speaker #3: Our liaison growth continues to be driven by the improvements we put in place in 2025, including best-in-class delivery times, a large catalog of liaisons, and new initiatives and strategies on liaison sales.

Speaker #3: Turning to slide 7, our recurring revenue continues to strengthen as our in-store instrument base expands. For all of 2025, recurring revenue represented 34% of total revenue and notably grew 21% year over year.

Speaker #3: We expect the recurring revenue proportion of total revenue will continue to grow steadily with increased cumulative instrument placements and to become an increasingly larger share of our business over time.

Wenbin Jiang: In bioinformatics, our software ecosystem continues to be a powerful growth driver. The advanced software embedded directly in our instruments, combined with the capabilities of the Cytek Cloud, are highly valued by our customers and are accelerating adoption of our products. By year-end 2025, the number of users on the Cytek Cloud grew to over 24,000, representing growth of more than 50% in a single year and unleashing nearly 8 users per installed FSP instrument. Our expanding digital footprint enhances the attractiveness of our offerings overall and helps to drive reagent revenue growth. Before turning to our financial results, I want to highlight the meaningful operational progress we achieved in 2025. Early in the year, we established a new manufacturing facility in Singapore and optimized our broader global operational footprint.

Speaker #3: In bioinformatics, our software ecosystem continues to be a powerful growth driver. The advanced software embedded directly in our instruments combined with the capabilities of the Cytek cloud are highly valued by our customers and are accelerating adoption of our products.

Speaker #3: Our year-end 2025, the number of users on the Cytek cloud grew to over 24,000, representing growth of more than 50% in a single year, and reaching nearly 8 users per in-store FSC instrument.

Speaker #3: Our expanding digital footprint enhances the attractiveness of our offerings overall and helps to drive liaison revenue growth. Before turning to our financial results, I want to highlight the meaningful operational progress we achieved in 2025.

Speaker #3: Earning the year, we established a new manufacturing facility in Singapore and optimized our broader global operational footprint. These actions strengthened our region-for-region manufacturing strategies and further reinforced the resilience of our supply chain.

Wenbin Jiang: These actions strengthened our region for region manufacturing strategy and further reinforced the resilience of our supply chain. I'm particularly proud that the Singapore site began generating revenue in less than 100 days from when we started the build out. Importantly, these initiatives also positioned us to mitigate the impact of the still evolving tariff policies worldwide. Now, I would like to ask Gil to review our financials.

Speaker #3: I'm particularly proud that the Singapore site again generating revenue in less than 100 days from when we started the build-out. Importantly, these initiatives also positioned us to mitigate the impact of the still-evolving tariff policies worldwide.

Speaker #3: Now, I would like to ask you to review our financials. Thanks, Wenden. Before I discuss the quarterly and full-year numbers, I want to comment on the macro trends we saw play out across the quarters of 2025.

[Company Representative] (Cytek Biosciences): Thanks, Wenbin. Before I discuss the quarterly and full year numbers, I want to comment on the macro trends we saw play out across the quarters of 2025. Beginning in Q1, macro uncertainties and weak demand resulted in total revenue declining 8% year-on-year. In Q2 and Q3, revenue growth stabilized with -2% and +2% growth, with growth in our service and APAC businesses being offset by declines, particularly in EMEA. In Q4, as we had expected, we saw EMEA stabilize while other markets continued to grow and overall revenue growth increased to 8%. We believe this turnaround is reflective of more durable trends in our markets as we have seen these trends continue into 2026, which has informed the full year 2026 guidance I will share with you in a moment. Turning to slide 8.

Bill McCombe: Thanks, Wenbin. Before I discuss the quarterly and full year numbers, I want to comment on the macro trends we saw play out across the quarters of 2025. Beginning in Q1, macro uncertainties and weak demand resulted in total revenue declining 8% year-on-year. In Q2 and Q3, revenue growth stabilized with -2% and +2% growth, with growth in our service and APAC businesses being offset by declines, particularly in EMEA. In Q4, as we had expected, we saw EMEA stabilize while other markets continued to grow and overall revenue growth increased to 8%. We believe this turnaround is reflective of more durable trends in our markets as we have seen these trends continue into 2026, which has informed the full year 2026 guidance I will share with you in a moment. Turning to slide 8.

Speaker #3: Beginning in the first quarter, macro uncertainties and weak demand resulted in total revenue declining 8% year-on-year. In Q2 and Q3, revenue growth stabilized with -2% and +2% growth.

Speaker #3: With growth in our service and APAC businesses being offset by declines, particularly in EMEA, then in Q4, as we had expected, we saw EMEA stabilize while other markets continued to grow and overall revenue growth increased to 8%.

Speaker #3: We believe this turnaround is reflective of more durable trends in our markets as we have seen these trends continue into 2026. Which has informed the full-year 2026 guidance I will share with you in a moment.

Speaker #3: Turning to slide 8, fourth quarter revenue was $62.1 million, up 8% year over year. Growth was driven by strong global performance in service and reagents, continued momentum in instrument demand across Asia-Pacific, and a rebound in EMEA instrument demand among academic and government customers.

[Company Representative] (Cytek Biosciences): Q4 revenue was $62.1 million, up 8% year-over-year. Growth was driven by strong global performance in service and reagents, continued momentum in instrument demand across Asia Pacific, and a rebound in EMEA instrument demand among academic and government customers. Currency movements were also a factor, contributing 3% to growth in the quarter. In the US, instrument revenue was flat as strength in academic and government offset softer demand from biotech and pharma. Globally in the quarter, revenue from academic and government customers grew 33% off a weak prior year comparison, while biopharma revenue declined 6% against a strong Q4 last year. Product revenue, which is comprised of instruments and reagents, increased 3% versus Q4 of 2024, driven by double-digit gains in APAC and EMEA, as well as a low single-digit gain in the US.

Bill McCombe: Q4 revenue was $62.1 million, up 8% year-over-year. Growth was driven by strong global performance in service and reagents, continued momentum in instrument demand across Asia Pacific, and a rebound in EMEA instrument demand among academic and government customers. Currency movements were also a factor, contributing 3% to growth in the quarter. In the US, instrument revenue was flat as strength in academic and government offset softer demand from biotech and pharma. Globally in the quarter, revenue from academic and government customers grew 33% off a weak prior year comparison, while biopharma revenue declined 6% against a strong Q4 last year. Product revenue, which is comprised of instruments and reagents, increased 3% versus Q4 of 2024, driven by double-digit gains in APAC and EMEA, as well as a low single-digit gain in the US.

Speaker #3: Currency movements were also a factor contributing 3% to growth in the quarter. In the US, instrument revenue was flat as strength in academic and government offset softer demand from biotech and pharma.

Speaker #3: Globally in the quarter, revenue from academic and government customers grew 33% off a week prior year comparison. While biopharma revenue declined 6% against a strong Q4 last year.

Speaker #3: Product revenue, which is comprised of instruments and reagents, increased 3% versus Q4 of 2024, driven by double-digit gains in APAC and EMEA, as well as a low single-digit gain in the US.

Speaker #3: US product revenue continued the stable trend from Q3. At tributable to a strong double-digit increase in instrument revenue from academic and government customers compared to a weak fourth quarter in 2024.

[Company Representative] (Cytek Biosciences): US product revenue continued the stable trend from Q3, attributable to a strong double-digit increase in instrument revenue from academic and government customers compared to a weak Q4 in 2024. This was offset by weakness in pharma biotech instrument sales in Q4 after their strong purchases in the Q3 of 2025. Our instrument sales in the US were supported by the launch of our new Aurora Evo instrument, as well as pent-up demand from, and stabilized funding of, academic and government customers. In EMEA, the situation was somewhat similar to the US. The double-digit percentage increase in EMEA product revenue was primarily driven by outsized gains in revenues from academic and government customers compared to a weak Q4 in 2024. Also similar to the US, EMEA revenue from pharma biotech was weak in Q4 compared to a strong year ago quarter.

Bill McCombe: US product revenue continued the stable trend from Q3, attributable to a strong double-digit increase in instrument revenue from academic and government customers compared to a weak Q4 in 2024. This was offset by weakness in pharma biotech instrument sales in Q4 after their strong purchases in the Q3 of 2025. Our instrument sales in the US were supported by the launch of our new Aurora Evo instrument, as well as pent-up demand from, and stabilized funding of, academic and government customers. In EMEA, the situation was somewhat similar to the US. The double-digit percentage increase in EMEA product revenue was primarily driven by outsized gains in revenues from academic and government customers compared to a weak Q4 in 2024. Also similar to the US, EMEA revenue from pharma biotech was weak in Q4 compared to a strong year ago quarter.

Speaker #3: This was offset by weakness in pharma biotech instrument sales in Q4 after their strong purchases in the third quarter of 2025. Our instrument sales in the US were supported by the launch of our new Aurora Evo instrument, as well as pent-up demand from, and stabilized funding of, academic and government customers.

Speaker #3: In EMEA, the situation was somewhat similar to the US. The double-digit percentage increase in EMEA product revenue was primarily driven by outsized gains in revenue from academic and government customers compared to a weak Q4 in 2024.

Speaker #3: Also similar to the US, EMEA revenue from pharma biotech was weak in Q4 compared to a strong year-ago quarter. While our reagent revenue is still a mid-single-digit percentage of our total revenue, it grew more than 20% in Q4 and more than 25% for all of 2025.

[Company Representative] (Cytek Biosciences): While our reagent revenue is still a mid-single digit percentage of our total revenue, it grew more than 20% in Q4 and more than 25% for all of 2025. As we've mentioned previously, this strong growth is due to a number of initiatives we implemented at the beginning of 2025, including attaining industry-leading delivery times, offering a large catalog of reagents, creating a new dedicated reagent sales team, and introducing new reagent products. Service continued to deliver strong recurring revenue growth with 25% growth in Q4 versus the prior year quarter. This was driven by growth in the installed base and active usage of our systems.

Bill McCombe: While our reagent revenue is still a mid-single digit percentage of our total revenue, it grew more than 20% in Q4 and more than 25% for all of 2025. As we've mentioned previously, this strong growth is due to a number of initiatives we implemented at the beginning of 2025, including attaining industry-leading delivery times, offering a large catalog of reagents, creating a new dedicated reagent sales team, and introducing new reagent products. Service continued to deliver strong recurring revenue growth with 25% growth in Q4 versus the prior year quarter. This was driven by growth in the installed base and active usage of our systems.

Speaker #3: As we've mentioned previously, this strong growth is due to a number of initiatives we implemented at the beginning of 2025, including attaining industry-leading delivery times, offering a large catalog of reagents, creating a new dedicated reagent sales team and introducing new reagent products.

Speaker #3: Service continued to deliver strong recurring revenue growth with 25% growth in Q4 versus the prior year quarter. This was driven by growth in the installed base and active usage of our systems.

Speaker #3: We expect service to continue to grow based on these factors, although its growth will slow gradually as the number of installed instruments grows, making the denominator larger in that calculation.

[Company Representative] (Cytek Biosciences): We expect service to continue to grow based on these factors, although its growth will slow gradually as the number of installed instruments grows, making the denominator larger in that calculation. Turning to geographic market performance, total US revenue grew 5% in Q4 versus prior year, driven by double-digit service revenue growth. EMEA grew 21% due to strength in service and instrument revenue from academic and government customers. APAC, including China, grew 15% in Q4, driven by growth in instrument service and reagents. GAAP gross profit was $32.9 million, a 2% decline versus the $33.7 million in Q4 of 2024. GAAP gross profit margin was 53% versus 59% in the prior year quarter.

Bill McCombe: We expect service to continue to grow based on these factors, although its growth will slow gradually as the number of installed instruments grows, making the denominator larger in that calculation. Turning to geographic market performance, total US revenue grew 5% in Q4 versus prior year, driven by double-digit service revenue growth. EMEA grew 21% due to strength in service and instrument revenue from academic and government customers. APAC, including China, grew 15% in Q4, driven by growth in instrument service and reagents. GAAP gross profit was $32.9 million, a 2% decline versus the $33.7 million in Q4 of 2024. GAAP gross profit margin was 53% versus 59% in the prior year quarter.

Speaker #3: Turning to geographic market performance, total U.S. revenue grew 5% in Q4 versus the prior year, driven by double-digit service revenue growth. EMEA grew 21% due to strength in service and instrument revenue from academic and government customers.

Speaker #3: APAC, including China, grew 15% in Q4, driven by growth in instrument service and reagents. Gap gross profit was 32.9 million a 2% decline versus the 33.7 million in Q4 of 2024.

Speaker #3: Gap gross profit margin was 53%, versus 59% in the prior year quarter. This was due to both a lower service gross margin resulting from an increase in headcount and travel costs, and a lower product gross margin as a result of higher materials and tariff costs and higher manufacturing overhead due to the duplicate costs from transitioning a production facility overseas.

[Company Representative] (Cytek Biosciences): This was due to both a lower service gross margin resulting from an increase in headcount and travel costs, and a lower product gross margin as a result of higher materials and tariff costs, and higher manufacturing overhead due to the duplicate cost from transitioning a production facility overseas. Adjusted gross profit margin, which excludes stock-based compensation and amortization of acquisition-related intangibles, was 55% in Q4, down from 61% in the prior-year quarter. Total operating expenses were $38.5 million in Q4, up $7.8 million or 25% versus Q4 of 2024, which included a non-recurring expense reduction of $2.6 million related to a change in estimate for a license and royalty settlement liability adjustment. Excluding this expense reduction, the increase was $5.2 million.

Bill McCombe: This was due to both a lower service gross margin resulting from an increase in headcount and travel costs, and a lower product gross margin as a result of higher materials and tariff costs, and higher manufacturing overhead due to the duplicate cost from transitioning a production facility overseas. Adjusted gross profit margin, which excludes stock-based compensation and amortization of acquisition-related intangibles, was 55% in Q4, down from 61% in the prior-year quarter. Total operating expenses were $38.5 million in Q4, up $7.8 million or 25% versus Q4 of 2024, which included a non-recurring expense reduction of $2.6 million related to a change in estimate for a license and royalty settlement liability adjustment. Excluding this expense reduction, the increase was $5.2 million.

Speaker #3: Adjusted gross profit margin, which excludes stock-based compensation and amortization of acquisition-related intangibles, was 55% in Q4, down from 61% in the prior year quarter.

Speaker #3: Total operating expenses were $38.5 million in Q4, up $7.8 million or 25% versus Q4 of 2024, which included a non-recurring expense reduction of $2.6 million related to a change in estimate for a license and royalties settlement liability adjustment.

Speaker #3: Excluding this expense reduction, the increase was $5.2 million; this was driven by higher general and administrative and sales and marketing expenses, partially offset by lower R&D.

[Company Representative] (Cytek Biosciences): This was driven by higher general and administrative and sales and marketing expenses, partially offset by lower R&D. Research and development expenses were $9 million, down 8% versus the year ago quarter, primarily due to lower headcount and compensation expenses and lower engineering expenses. Sales and marketing expenses were $13.1 million, up 11% versus the year ago quarter, due to higher headcount and compensation expenses and higher sales commissions. General and administrative expenses were $16.4 million, up $7.3 million from the year ago quarter, which included the $2.6 million reduction I mentioned before. Excluding this reduction, the increase would have been $4.7 million or 40%. The increase was primarily attributable to legal expenses related to a patent litigation case and higher compensation, software, and bad debt expenses.

Bill McCombe: This was driven by higher general and administrative and sales and marketing expenses, partially offset by lower R&D. Research and development expenses were $9 million, down 8% versus the year ago quarter, primarily due to lower headcount and compensation expenses and lower engineering expenses. Sales and marketing expenses were $13.1 million, up 11% versus the year ago quarter, due to higher headcount and compensation expenses and higher sales commissions. General and administrative expenses were $16.4 million, up $7.3 million from the year ago quarter, which included the $2.6 million reduction I mentioned before. Excluding this reduction, the increase would have been $4.7 million or 40%. The increase was primarily attributable to legal expenses related to a patent litigation case and higher compensation, software, and bad debt expenses.

Speaker #3: Research and development expenses were 9 million down 8% versus the year-ago quarter, primarily due to lower headcount and compensation expenses and lower engineering expenses.

Speaker #3: Sales and marketing expenses were 13.1 million up 11% versus the year-ago quarter, due to higher headcount and compensation expenses and higher sales commissions. General and administrative expenses were 16.4 million up 7.3 million from the year-ago quarter, which included the 2.6 million reduction I mentioned before.

Speaker #3: Excluding this reduction, the increase would have been $4.7 million, or 40%. The increase was primarily attributable to legal expenses related to a patent litigation case and higher compensation, software, and bad debt expenses.

[Company Representative] (Cytek Biosciences): Loss from operations was $5.6 million for Q4 versus a $3 million income from operations in the year-ago quarter, which included the $2.6 million non-recurring expense reduction that I mentioned before. Excluding this amount, income from operations in Q4 2024 would have been $0.3 million. The remaining decline in income from operations of $5.9 million was due to $0.8 million lower gross profit and $5.2 million higher operating expenses. Net loss in Q4 was $44.1 million versus net income of $9.6 million in the prior year quarter. The current quarter net loss of $44.1 million included the recording of a $38.1 million valuation allowance or write-off against deferred tax assets under ASC 740 due to the uncertainty of realizing the associated future tax benefits.

Bill McCombe: Loss from operations was $5.6 million for Q4 versus a $3 million income from operations in the year-ago quarter, which included the $2.6 million non-recurring expense reduction that I mentioned before. Excluding this amount, income from operations in Q4 2024 would have been $0.3 million. The remaining decline in income from operations of $5.9 million was due to $0.8 million lower gross profit and $5.2 million higher operating expenses. Net loss in Q4 was $44.1 million versus net income of $9.6 million in the prior year quarter. The current quarter net loss of $44.1 million included the recording of a $38.1 million valuation allowance or write-off against deferred tax assets under ASC 740 due to the uncertainty of realizing the associated future tax benefits.

Speaker #3: Loss from operations was 5.6 million for Q4 versus a 3 million income from operations in the year-ago quarter. Which included the 2.6 million non-recurring expense reduction that I mentioned before.

Speaker #3: Excluding this amount, income from operations in Q4 2024 would have been 0.3 million. The remaining decline in income from operations of 5.9 million was due to 0.8 million lower gross profit and 5.2 million higher operating expenses.

Speaker #3: Net loss in Q4 was 44.1 million versus net income of 9.6 million in the prior year quarter. The current quarter net loss of 44.1 million included the recording of a 38.1 million valuation allowance or write-off against the third tax assets under ASC 740, due to the uncertainty of realizing the associated future tax benefits.

Speaker #3: This is solely an accounting determination that does not affect our ability to use these losses for tax purposes and is a non-cash item. Moreover, it is an unusually large amount, as these deferred tax assets had been accumulated over multiple years and this was the first time such a valuation allowance had been taken.

[Company Representative] (Cytek Biosciences): This is solely an accounting determination that does not affect our ability to use these losses for tax purposes and is a non-cash item. Moreover, it is an unusually large amount as these deferred tax assets had been accumulated over multiple years and this was the first time such a valuation allowance had been taken. Excluding this valuation allowance, the net loss would have been $6.0 million. Net income in Q4 2024 included a non-recurring benefit of $6.7 million after tax associated with the settlement liability adjustment I mentioned before. Excluding this item, net income would have been $2.9 million.

Bill McCombe: This is solely an accounting determination that does not affect our ability to use these losses for tax purposes and is a non-cash item. Moreover, it is an unusually large amount as these deferred tax assets had been accumulated over multiple years and this was the first time such a valuation allowance had been taken. Excluding this valuation allowance, the net loss would have been $6.0 million. Net income in Q4 2024 included a non-recurring benefit of $6.7 million after tax associated with the settlement liability adjustment I mentioned before. Excluding this item, net income would have been $2.9 million.

Speaker #3: Excluding this valuation allowance, the net loss would have been 6.0 million. Net income in Q4 2024 included a non-recurring benefit of 6.7 million after tax associated with the settlement liability adjustment I mentioned before.

Speaker #3: Excluding this item, net income would have been 2.9 million. The remaining increase in net loss of 8.9 million was primarily due to 0.8 million lower gross profit; the 5.2 million increase in operating expenses; and a 2.5 million increase in other tax expense principally on foreign earnings.

[Company Representative] (Cytek Biosciences): The remaining increase in net loss of $8.9 million was primarily due to $0.8 million lower gross profit, the $5.2 million increase in operating expenses, and a $2.5 million increase in other tax expense, principally on foreign earnings. Adjusted EBITDA, which excludes the stock-based compensation and foreign exchange impact, declined to $4.5 million from $12.5 million in the year ago quarter, which included the $2.6 million non-recurring benefit I described above. Excluding this amount, adjusted EBITDA in Q4 2024 would have been $9.9 million. The decline of $5.4 million was primarily due to higher operating expenses of $5.2 million and lower gross profit of $0.8 million.

Bill McCombe: The remaining increase in net loss of $8.9 million was primarily due to $0.8 million lower gross profit, the $5.2 million increase in operating expenses, and a $2.5 million increase in other tax expense, principally on foreign earnings. Adjusted EBITDA, which excludes the stock-based compensation and foreign exchange impact, declined to $4.5 million from $12.5 million in the year ago quarter, which included the $2.6 million non-recurring benefit I described above. Excluding this amount, adjusted EBITDA in Q4 2024 would have been $9.9 million. The decline of $5.4 million was primarily due to higher operating expenses of $5.2 million and lower gross profit of $0.8 million.

Speaker #3: Adjusted EBITDA, which excludes the stock-based compensation and foreign exchange impacts, declined to 4.5 million from 12.5 million in the year-ago quarter, which included the 2.6 million non-recurring benefit I described above.

Speaker #3: Excluding this amount, adjusted EBITDA in Q4 2024 would have been 9.9 million. The decline of 5.4 million was primarily due to higher operating expenses of 5.2 million and lower gross profit of 0.8 million.

[Company Representative] (Cytek Biosciences): Free cash flow during Q4 2025 was slightly negative at -$0.2 million, modestly decreasing our total cash and marketable securities to $261.5 million at 31 December 2025, from $261.7 million at the end of Q3. Now turning to slide 9 for the full year 2025. Total revenue for the year ended 31 December 2025 was $201.5 million, a 1% increase over the prior year. The increase in total revenue in 2025 was primarily driven by a 21% growth in worldwide service revenue and double-digit growth in APAC product revenue, offset by a slowdown in EMEA and US product revenue.

Bill McCombe: Free cash flow during Q4 2025 was slightly negative at -$0.2 million, modestly decreasing our total cash and marketable securities to $261.5 million at 31 December 2025, from $261.7 million at the end of Q3. Now turning to slide 9 for the full year 2025. Total revenue for the year ended 31 December 2025 was $201.5 million, a 1% increase over the prior year. The increase in total revenue in 2025 was primarily driven by a 21% growth in worldwide service revenue and double-digit growth in APAC product revenue, offset by a slowdown in EMEA and US product revenue.

Speaker #3: Free cash flow during Q4 2025 was slightly negative at minus 0.2 million; modestly decreasing our total cash and marketable securities to 261.5 million at December 31, 2025, from 261.7 million at the end of the third quarter.

Speaker #3: Now turning to slide 9 for the full year 2025. Total revenue for the year ended December 31, 2025, was 201.5 million, a 1% increase over the prior year.

Speaker #3: The increase in total revenue in 2025 was primarily driven by a 21% growth in worldwide service revenue and double-digit growth in APAC product revenue offset by a slowdown in EMEA and US product revenue.

Speaker #3: Gap gross profit was 104.5 million for 2025, a decrease of 6% compared to a gap gross profit of 111.1 million in the prior year.

[Company Representative] (Cytek Biosciences): GAAP gross profit was $104.5 million for 2025, a decrease of 6% compared to a GAAP gross profit of $111.1 million in the prior year. GAAP gross margin was 52% for 2025, compared to 55% in the prior year. The decline was primarily due to higher service headcount and material costs, higher tariffs, and higher manufacturing overhead costs due to transitioning the production facility overseas, as I mentioned before. Adjusted gross margin, which excludes stock-based compensation and acquisition-related intangibles for 2025, was 55%, down from 59% in the prior year. Operating expenses were $144.8 million for 2025, compared to operating expenses of $131.6 million in the prior year, which included the non-recurring reduction of $2.6 million I described before.

Bill McCombe: GAAP gross profit was $104.5 million for 2025, a decrease of 6% compared to a GAAP gross profit of $111.1 million in the prior year. GAAP gross margin was 52% for 2025, compared to 55% in the prior year. The decline was primarily due to higher service headcount and material costs, higher tariffs, and higher manufacturing overhead costs due to transitioning the production facility overseas, as I mentioned before. Adjusted gross margin, which excludes stock-based compensation and acquisition-related intangibles for 2025, was 55%, down from 59% in the prior year. Operating expenses were $144.8 million for 2025, compared to operating expenses of $131.6 million in the prior year, which included the non-recurring reduction of $2.6 million I described before.

Speaker #3: Gap gross margin was 52% for 2025 compared to 55% in the prior year. The decline was primarily due to the higher service headcount and material costs; higher tariffs and higher manufacturing overhead costs due to transitioning the production facility overseas as I mentioned before.

Speaker #3: Adjusted gross margin, which excludes stock-based compensation and acquisition-related intangibles, for 2025 was 55%, down from 59% in the prior year. Operating expenses were $144.8 million for 2025, compared to operating expenses of $131.6 million in the prior year, which included the non-recurring reduction of $2.6 million I described before.

Speaker #3: Excluding this reduction and a non-recurring ATM offering cost write-off in Q3 2025, the increase would have been 9.9 million or 7%. This was primarily due to higher G&A costs offset by lower R&D costs.

[Company Representative] (Cytek Biosciences): Excluding this reduction and a non-recurring ATM offering cost write-off in Q3 2025, the increase would have been $9.9 million, or 7%. This was primarily due to higher G&A costs offset by lower R&D costs. Research and development expenses were $36.5 million, down from $39.4 million, or 7% versus the year-ago quarter, primarily due to lower headcount and engineering expense. Sales and marketing expenses were $49.4 million, up 1% versus the $49.1 million in the year-ago quarter. General and administrative expenses were $58.9 million versus the $43.1 million in the year-ago quarter, which included the $2.6 million reduction I mentioned before. Excluding this reduction and the non-recurring offering cost write-off, the increase would have been $12.5 million or 27%.

Bill McCombe: Excluding this reduction and a non-recurring ATM offering cost write-off in Q3 2025, the increase would have been $9.9 million, or 7%. This was primarily due to higher G&A costs offset by lower R&D costs. Research and development expenses were $36.5 million, down from $39.4 million, or 7% versus the year-ago quarter, primarily due to lower headcount and engineering expense. Sales and marketing expenses were $49.4 million, up 1% versus the $49.1 million in the year-ago quarter. General and administrative expenses were $58.9 million versus the $43.1 million in the year-ago quarter, which included the $2.6 million reduction I mentioned before. Excluding this reduction and the non-recurring offering cost write-off, the increase would have been $12.5 million or 27%.

Speaker #3: Research and development expenses were 36.5 million down from 39.4 million or 7% versus the year-ago quarter, primarily due to lower headcount and engineering expense.

Speaker #3: Sales and marketing expenses were $49.4 million, up 1% versus the $49.1 million in the year-ago quarter. General and administrative expenses were $58.9 million versus the $43.1 million in the year-ago quarter, which included the $2.6 million reduction I mentioned before.

Speaker #3: Excluding this reduction and the non-recurring offering cost write-off, the increase would have been 12.5 million or 27%. The increase was primarily attributable to higher legal expenses related to the patent litigation case I mentioned before, higher compensation, sales, and use tax, and software expenses.

[Company Representative] (Cytek Biosciences): The increase was primarily attributable to higher legal expenses related to the patent litigation case I mentioned before, higher compensation, sales and use tax, and software expenses. Loss from operations in 2025 was $40.4 million, which included a $0.7 million non-recurring deferred ATM facility offering costs write-off. This compares to a loss of $20.5 million in 2024 or $23.1 million, excluding the $2.6 million non-recurring expense reduction I described before. Excluding both these non-recurring items, the loss from operations increased by $16.6 million, which was due to $6.6 million lower gross profit and $9.9 million higher operating expenses. GAAP net loss for the year ended 31 December 2025 was $66.5 million.

Bill McCombe: The increase was primarily attributable to higher legal expenses related to the patent litigation case I mentioned before, higher compensation, sales and use tax, and software expenses. Loss from operations in 2025 was $40.4 million, which included a $0.7 million non-recurring deferred ATM facility offering costs write-off. This compares to a loss of $20.5 million in 2024 or $23.1 million, excluding the $2.6 million non-recurring expense reduction I described before. Excluding both these non-recurring items, the loss from operations increased by $16.6 million, which was due to $6.6 million lower gross profit and $9.9 million higher operating expenses. GAAP net loss for the year ended 31 December 2025 was $66.5 million.

Speaker #3: Loss from operations in 2025 was 40.4 million, which included a 0.7 million non-recurring deferred ATM facility offering cost write-off. This compares to a loss of 20.5 million in 2024 or 23.1 million excluding the 2.6 million non-recurring expense reduction I described before.

Speaker #3: Excluding both these non-recurring items, the loss from operations increased by 16.6 million which was due to 6.6 million lower gross profit and 9.9 million higher operating expenses.

Speaker #3: Gap net loss for the year ended December 31, 2025, was 66.5 million. This included the recording of a 33.1 million valuation allowance or write-off against deferred tax assets as I described before, in relation to Q4, due to the uncertainty of realizing the associated future tax benefits.

[Company Representative] (Cytek Biosciences): This included the recording of a $33.1 million valuation allowance or write-off against deferred tax assets, as I described before in relation to Q4, due to the uncertainty of realizing the associated future tax benefits. As mentioned before, this was an unusually large amount due to the first-time nature of this allowance. The GAAP net loss also included the $0.7 million non-recurring offering cost write-off mentioned earlier. Excluding these items, GAAP net loss for 2025 would have been $32.7 million compared to a net loss of $6 million or $12.7 million, excluding the $6.7 million non-recurring benefit from the settlement liability adjustment described before. Excluding these non-recurring items, GAAP net loss increased by $20 million in 2025.

Bill McCombe: This included the recording of a $33.1 million valuation allowance or write-off against deferred tax assets, as I described before in relation to Q4, due to the uncertainty of realizing the associated future tax benefits. As mentioned before, this was an unusually large amount due to the first-time nature of this allowance. The GAAP net loss also included the $0.7 million non-recurring offering cost write-off mentioned earlier. Excluding these items, GAAP net loss for 2025 would have been $32.7 million compared to a net loss of $6 million or $12.7 million, excluding the $6.7 million non-recurring benefit from the settlement liability adjustment described before. Excluding these non-recurring items, GAAP net loss increased by $20 million in 2025.

Speaker #3: As mentioned before, this was an unusually large amount due to the first-time nature of this allowance. The GAAP net loss also included the $0.7 million non-recurring offering cost write-off mentioned earlier.

Speaker #3: Excluding these items, gap net loss for 2025 would have been 32.7 million compared to a net loss of 6 million or 12.7 million excluding the 6.7 million non-recurring benefit from the settlement liability adjustment described before.

Speaker #3: Excluding these non-recurring items, GAAP net loss increased by $20 million in 2025. This was due to $6.6 million lower gross profit, $9.9 million higher operating expenses, and $3.3 million higher taxes, mainly on foreign earnings.

[Company Representative] (Cytek Biosciences): This was due to $6.6 million lower gross profit, $9.9 million higher operating expenses, and $3.3 million higher taxes, mainly on foreign earnings. Adjusted EBITDA was $5 million in 2025, which excludes the non-recurring items mentioned earlier, foreign exchange impacts, and stock-based compensation expense. This compared to $22.4 million in 2024. The decline of $17.4 million was primarily due to $6.6 million lower gross profit, $9.9 million higher operating expenses, and $2.3 million lower stock-based compensation. Adjusted EBITDA excluding investment income declined from $14.4 million in 2024 to a negative $3.1 million in 2025. Consistent with our historical focus on cost control and profitability, we are committed to improving these metrics going forward.

Bill McCombe: This was due to $6.6 million lower gross profit, $9.9 million higher operating expenses, and $3.3 million higher taxes, mainly on foreign earnings. Adjusted EBITDA was $5 million in 2025, which excludes the non-recurring items mentioned earlier, foreign exchange impacts, and stock-based compensation expense. This compared to $22.4 million in 2024. The decline of $17.4 million was primarily due to $6.6 million lower gross profit, $9.9 million higher operating expenses, and $2.3 million lower stock-based compensation. Adjusted EBITDA excluding investment income declined from $14.4 million in 2024 to a negative $3.1 million in 2025. Consistent with our historical focus on cost control and profitability, we are committed to improving these metrics going forward.

Speaker #3: Adjusted EBITDA was $5 million in 2025, which excludes the non-recurring items mentioned earlier, foreign exchange impacts, and stock-based compensation expense. This compared to $22.4 million in 2024.

Speaker #3: The decline of 17.4 million was primarily due to 6.6 million lower gross profit, 9.9 million higher operating expenses, and 2.3 million lower stock-based compensation.

Speaker #3: Adjusted EBITDA excluding investment income declined from 14.4 million in 2024 to a negative 3.1 million in 2025. Consistent with our historical focus on cost control and profitability, we are committed to improving these metrics going forward.

[Company Representative] (Cytek Biosciences): Cash, cash equivalents and marketable securities totaled $261.5 million as of 31 December 2025. This represents a decrease of $16.4 million from the $277.9 million at the end of December 2024, in part reflecting the repurchase of $15.1 million of Cytek's stock in our stock repurchase program during 2025. This $15.1 million repurchased approximately 3.3 million shares at a weighted average cost of $4.58 per share, leaving us with 128.6 million shares outstanding as of 31 December 2025. Our strong balance sheet and positive cash generation underscore our ability to invest in our global growth initiatives. Turning to our full year guidance on slide 10.

Bill McCombe: Cash, cash equivalents and marketable securities totaled $261.5 million as of 31 December 2025. This represents a decrease of $16.4 million from the $277.9 million at the end of December 2024, in part reflecting the repurchase of $15.1 million of Cytek's stock in our stock repurchase program during 2025. This $15.1 million repurchased approximately 3.3 million shares at a weighted average cost of $4.58 per share, leaving us with 128.6 million shares outstanding as of 31 December 2025. Our strong balance sheet and positive cash generation underscore our ability to invest in our global growth initiatives. Turning to our full year guidance on slide 10.

Speaker #3: Cash cash equivalents and marketable securities totaled 261.5 million as of December 31, 2025. This represents a decrease of 16.4 million from the 277.9 million at the end of December 2024, in part reflecting the repurchase of 15.1 million of Cytek stock in our stock repurchase program during 2025.

Speaker #3: This 15.1 million repurchased approximately 3.3 million shares at a weighted average cost of $4.58 per share, leaving us with 128.6 million shares outstanding as of December 31, 2025.

Speaker #3: Our strong balance sheet and positive cash generation underscore our ability to invest in our global growth initiatives. Turning to our full-year guidance on slide 10, we are initiating our 2026 revenue outlook at 205 million to 212 million assuming constant currency exchange rates.

[Company Representative] (Cytek Biosciences): We are initiating our 2026 revenue outlook at $205 million to $212 million, assuming constant currency exchange rates. We are also not assuming any significant benefit at this time from changes in the tariff environment going forward. This guidance range reflects the improved market environment in EMEA and the US and continued strong growth in APAC instruments and in our service and re-aging businesses globally. We expect these dynamics to continue. Importantly, we continue to believe our performance in Q4 and full year 2025 reflects a strong market leadership position in what has been a difficult environment. Our core business is now showing positive growth in all major regions and our recurring revenue continues to grow. Notwithstanding some temporarily elevated operating expenses, we delivered positive adjusted EBITDA for full year 2025, which we anticipate will continue in 2026.

Bill McCombe: We are initiating our 2026 revenue outlook at $205 million to $212 million, assuming constant currency exchange rates. We are also not assuming any significant benefit at this time from changes in the tariff environment going forward. This guidance range reflects the improved market environment in EMEA and the US and continued strong growth in APAC instruments and in our service and re-aging businesses globally. We expect these dynamics to continue. Importantly, we continue to believe our performance in Q4 and full year 2025 reflects a strong market leadership position in what has been a difficult environment. Our core business is now showing positive growth in all major regions and our recurring revenue continues to grow. Notwithstanding some temporarily elevated operating expenses, we delivered positive adjusted EBITDA for full year 2025, which we anticipate will continue in 2026.

Speaker #3: We are also not assuming any significant benefit at this time from changes in the tariff environment going forward. This guidance range reflects the improved market environment in EMEA and the US and continued strong growth in APAC instruments, and in our service and reaging businesses globally.

Speaker #3: We expect these dynamics to continue. Importantly, we continue to believe our performance in Q4 and full-year 2025 reflects a strong market leadership position in what has been a difficult environment.

Speaker #3: Our core business is now showing positive growth in all major regions and our recurring revenue continues to grow. Notwithstanding some temporarily elevated operating expenses, we delivered positive adjusted EBITDA for full-year 2025, which we anticipate will continue in 2026.

Speaker #3: As we've done previously, we believe we will continue to perform well relative to the overall flow cytometry market, which is also beginning to show signs of stabilization.

[Company Representative] (Cytek Biosciences): As we've done previously, we believe we will continue to perform well relative to the overall flow cytometry market, which is also beginning to show signs of stabilization. With that, I will turn it back over to Wenbin.

Bill McCombe: As we've done previously, we believe we will continue to perform well relative to the overall flow cytometry market, which is also beginning to show signs of stabilization. With that, I will turn it back over to Wenbin.

Speaker #3: With that, I will turn it back over to Wenden. Thanks, Bill. Turning to slide 11. I want to close by thanking our Cytek team.

Wenbin Jiang: Thanks, Bill. Turning to slide 11. I want to close by thanking our Cytek team. This year, we were recognized as a public company growth leader in America by TIME magazine. This validation is a testament to Cytek's outstanding record of growth and innovation over the last five years. Overall, I believe our Q4 and full year performance during a challenging 2025 reflects the resilience of our organization and the strength of our leadership in the flow cytometry market. Our broad-based execution positions us well for 2026, where our priorities remain focused on driving the market penetration of our instrument platforms, continuing to advance our technological leadership with innovative new products, driving the growth of our recurring revenue lines, and delivering profitable, sustainable growth. I want to thank everyone for joining today's call, and we will now open it up for questions. Operator.

Speaker #3: This year, we were recognized as a public company growth leader in America by Time Magazine. This validation is a testament to Cytek's outstanding record of growth and innovation over the last five years.

Speaker #3: Overall, I believe our fourth quarter and full-year performance during a challenging 2025 reflects the resilience of our organization and the strength of our leadership in the flow cytometry market.

Speaker #3: Our broad-based execution positions as well for 2026, where our priorities remain focused on driving the market penetration of our instrument platforms, continuing to advance our technological leadership with innovative new products driving the growth of our recurring revenue lines and delivering profitable, sustainable growth.

Speaker #3: I want to thank everyone for joining today's call, and we will now open up for questions. After that.

Operator: As a reminder, to ask a question, simply press star one on your telephone keypad. Again, that is star one to ask a question. From TD Cowen, our first question comes from the line of Brendan Smith. Please go ahead.

Speaker #1: As a reminder to ask a question, simply press star one on your telephone keypad. Again, that is star one to ask a question. And from TD Cohen, our first question comes from the line of Brendan Smith.

Speaker #1: Please go ahead.

Speaker #3: Great. Thanks for taking the questions, guys. I appreciate all the color. I actually wanted to maybe ask a little bit higher-level question. Just about some of the underlying assumptions of the growth of the overall flow cytometry market.

Brendan Smith: Great. Thanks for taking the questions, guys. I appreciate all the color. I actually wanted to maybe ask a little bit higher level question, just about some of the underlying assumptions of the growth of the overall flow cytometry market. You guys gave a lot of good color on different end market breakdowns. I think we've seen, you know, something like 8% to 9% CAGR maybe up to 2031 or 32, if I'm not mistaken. I guess irrespective of that exact number, do you have a sense, kind of giving your global exposure there of relative end market breakdown of that growth? I guess maybe better put, you know, are there geographic considerations for expansion of the market that you think you'd be better positioned to capitalize on, just especially given your strength in APAC?

Speaker #3: You guys gave a lot of good color on different end market breakdown. And I think we've seen something like 8 to 9 percent CAGR maybe up to 2031 or '32, if I'm not mistaken.

Speaker #3: But I guess irrespective of that exact number, do you have a sense kind of of given your global exposure there of relative end market breakdown of that growth?

Speaker #3: And I guess maybe better put, are there geographic considerations for expansion of the market that you think you'd be maybe better positioned to capitalize on, just especially given your strength in APAC?

Speaker #3: Just kind of wondering how you're thinking about that overall. Thanks, guys.

Brendan Smith: Just kind of wondering how you're thinking about that overall. Thanks, guys.

Speaker #4: Yeah, I think hi, Brendan. This is Bill. I think we've seen consistent double-digit growth in the market in APAC. Or at least in our revenues in APAC.

[Company Representative] (Cytek Biosciences): Yeah, I think, hi, Brendan, this is Bill. I think, you know, we've seen consistent double-digit growth in the market in Asia Pacific, or at least in our revenues in Asia Pacific. We may have done a little better than the market, particularly, you know, given our growth in sorters and the Aurora franchise. I, you know, our sense is that there's a decent mid-single digits, mid-upper single digits growth in that market, in that region. In, I, we think that Europe has probably been the slowest market, certainly has been for us.

Bill McCombe: Yeah, I think, hi, Brendan, this is Bill. I think, you know, we've seen consistent double-digit growth in the market in Asia Pacific, or at least in our revenues in Asia Pacific. We may have done a little better than the market, particularly, you know, given our growth in sorters and the Aurora franchise. I, you know, our sense is that there's a decent mid-single digits, mid-upper single digits growth in that market, in that region. In, I, we think that Europe has probably been the slowest market, certainly has been for us.

Speaker #4: We may have done a little better than the market. Particularly given our growth in sorters and the Aurora franchise. So but our sense is that there's a decent mid-single digits, mid-upper single digits growth in that market, in that region.

Speaker #4: In we think that Europe has probably been the slowest market, certainly has been for us. And the US falls somewhere in between. We recorded we think we've done better than the market overall in the US and in EMEA.

Bill McCombe: The US falls somewhere in between. We think we've done better than the market overall in the US and in EMEA. Hard to really estimate what the market's doing in those regions. You know, we've seen some negative growth by some of our competitors, it's hard to extrapolate. Wenbin, do you have any other comments?

Speaker #4: Hard to really estimate what the market's doing in those regions that we've seen some negative growth by some of our competitors, but it's hard to extrapolate.

Speaker #4: Wenbin, do you have any other comments?

Speaker #3: No, I think that's summarized as well.

Wenbin Jiang: No, I think that summarizes well.

Speaker #4: And look, I think we're in a the market growth rates that we've seen in the last couple of years have certainly been below most of the estimates that we most of the market studies for five-year growth for flow cytometry call for a growth rates that are in the high single digits and on a global basis.

Bill McCombe: Look, I think, you know, the market growth rates that we've seen in the last couple years have certainly been below most of the estimates. Most of the market studies for five-year growth for flow cytometry call for growth rates that are in the high single digits on a global basis. We obviously have been temporarily below that for the last couple of years. You know, we expect it to rebound.

Speaker #4: And we obviously have been temporarily below that for the last couple of years, but we expect it to rebound.

Speaker #3: Got it. Makes sense. Thanks, guys.

[Analyst] (TD Cowen): Got it. Makes sense. Thanks, guys.

Brendan Smith: Got it. Makes sense. Thanks, guys.

Operator: From Piper Sandler, our next question comes from the line of David Westenberg. Please go ahead.

Speaker #1: From Piper Sandler, our next question comes from the line of David Westenberg. Please go ahead.

Sky: Hi, this is Sky on for Dave. Thanks for taking the question. Just to start off, what was the end of year growth acceleration? What was that driven by? Was it primarily academic budget cycles? Are you seeing a recovery in pharma spending, and how should we think about budgets for 2026? Thanks.

Sky Stein: Hi, this is Sky on for Dave. Thanks for taking the question. Just to start off, what was the end of year growth acceleration? What was that driven by? Was it primarily academic budget cycles? Are you seeing a recovery in pharma spending, and how should we think about budgets for 2026? Thanks.

Speaker #5: Hi, this is Sky on for Dave. Thanks for taking the question. Just to start off, what was acceleration? What was that driven by? Was it primarily academic budget cycles, or are you seeing a recovery in pharma spending, and how should we think about budgets for 2026?

Speaker #5: Thanks.

Bill McCombe: We saw, as I mentioned in my remarks, an improving environment across each of the quarters of 2025. The Q1 was, you know, not so great with -8% revenue growth. We saw stabilization going back to -2 in Q2, +2 in Q3, and then +8 in Q4. I think that was driven by a normalization, a combination of a normalization in the academic and government spending market. We saw some catch-up disbursements from the NIH and we think some catch-up spending that had been deferred from earlier in the year. All those factors were at play. We also had a currency benefit in EMEA.

Speaker #4: We think there was that we saw, as I mentioned in my remarks, an improving environment across each of the quarters of 2025. So the first quarter was not so great with minus 8 percent revenue growth.

Speaker #4: And then we saw a stabilization going back to minus 2 in Q2, plus 2 in Q3, and then plus 8 in Q4. And I think that was driven by a normalization, a combination of a normalization in the academic and government spending market.

Speaker #4: We saw some catch-up disbursements from the NIH, and we think some catch-up spending that had been deferred from earlier in the year. So all those factors were at play.

Speaker #4: We also had a currency benefit in EMEA. So when we look, we put all that together, we think that the uncertainties that impacted the markets in the first part of 2025, particularly the first quarter, seem to have receded and we're seeing improving.

Bill McCombe: When we look, we put all that together, we think that the uncertainties that impacted the markets in the first part of 2025, particularly Q1, seem to have receded. We're seeing improving... Particularly strong academic and government quarter in Q4. You know, we think, as I said, there's a combination there of just a fundamentally improved sentiment and some catch-up, and we're assuming a continuation of that more positive environment in our guidance.

Speaker #4: Particularly strong academic and government quarter in the fourth quarter. And we think, as I said, there's a combination there of just a fundamentally improved sentiment and some catch-up.

Speaker #4: And we're expecting we're assuming a continuation of that more positive environment in our guidance.

Speaker #3: Yeah, globally, academic and government sectors have done well. And in Q4.

Wenbin Jiang: Globally, academic and government sectors have done well in Q4.

Bill McCombe: Yeah. We saw 5% growth in academic and government for the full year, and 9% in the second half. That's across both our product and service businesses. That second half, you know, growth is, in academic and government is obviously pretty solid.

Speaker #4: Yeah, we saw. 5 percent growth in academic and government for the full year and 9 percent in the second half. And that's across both our product and service businesses.

Speaker #4: So that second half growth is in academic and government is obviously pretty solid.

Speaker #1: Very helpful. Thank you. And just lastly, what was the mix in 2025 between new customer acquisitions versus existing customers maybe expanding their capacity and do you have any idea where you might see this mix for 2026?

Sky: Very helpful. Thank you. Just lastly, what was the mix in 2025 between new customer acquisitions versus existing customers maybe expanding their capacity? Do you have any idea where you might see this mix for 2026? Thanks.

Sky Stein: Very helpful. Thank you. Just lastly, what was the mix in 2025 between new customer acquisitions versus existing customers maybe expanding their capacity? Do you have any idea where you might see this mix for 2026? Thanks.

Speaker #1: Thanks.

Speaker #4: Yeah, we don't really break out those statistics. Just to say it's a combination of both. We have a lot of customers who have purchased multiple systems and continuing to prefer our technology.

Bill McCombe: Yeah, we don't really break out those statistics, just to say it's a combination of both. You know, we have a lot of customers who have purchased multiple systems and continue to prefer our technology. Pharma companies, as we've indicated in the past, once they make a technology choice, they tend to stick with it. We're also seeing conversions from competitive systems.

Speaker #4: Pharma companies, as we've indicated in the past, once they make a technology choice, they tend to stick with it. But then we're also seeing conversions from competitor systems.

Operator: From Stephens, our next question comes from the line of Mason Carrico. Please go ahead.

Speaker #1: From Stevens, our next question comes from the line of Mason Caraco. Please go ahead.

Speaker #5: Hey, good afternoon. Thanks for taking the questions. This is Ben on for Mason. How are you thinking about maybe your commercial investments in 2026?

Ben: Hi. Good afternoon. Thanks for taking the questions. This is Ben on for Mason. How are you thinking about, maybe your commercial investments in 2026? Are you comfortable with the size of the sales teams today? Is there anywhere you're looking to invest in the next year?

Ben Hendrix: Hi. Good afternoon. Thanks for taking the questions. This is Ben on for Mason. How are you thinking about, maybe your commercial investments in 2026? Are you comfortable with the size of the sales teams today? Is there anywhere you're looking to invest in the next year?

Speaker #5: Are you comfortable with the size of the sales teams today? And is there anywhere you're looking to invest in the next year?

Speaker #4: Yeah, overall, as you can see, we have been focused on high-end of the market segment and represented by the products like Aurora Evo and Aurora Cell Soda, which grew double-digit last year and in Q4.

Wenbin Jiang: Yeah. Overall, as you can see, we have been focused on high end of the market segment and represented by the products like Aurora Evo or Aurora CS, which grew double digits last year and in Q4. Now, on the commercial side, clearly, and we are reviewing and the segment, we are clearly weak, and we are going to continue to invest in those segments to drive the future revenue growth.

Speaker #4: And now, on the commercial side, clearly, and we are reviewing and the segment, we are clearly weak. And we are going to continue to invest in those segments to drive the future revenue growth.

Speaker #5: Yeah, we have also made investments in our reagent sales force as well. So the commercial side will continue to be an area of focus for investment.

Bill McCombe: Yeah. We have also made investments in our reagent sales force as well, so the commercial side will be continued to be an area of focus for investment.

Speaker #3: Got it. Thank you. And then what's your willingness to be flexible on pricing this year to help drive instrument placements?

[Analyst] (TD Cowen): Got it. Thank you. Then what's your willingness to be flexible on pricing this year to help drive instrument placements?

Ben Hendrix: Got it. Thank you. Then what's your willingness to be flexible on pricing this year to help drive instrument placements?

Wenbin Jiang: To Cytek, pricing is always market driven, and our cost structure is very competitive, and we can deal with any situations and as needed.

Speaker #4: To cite it, pricing is always market-driven. And we are our cost structure is very competitive, and we can deal with any situations and as needed.

Wenbin Jiang: To Cytek, pricing is always market driven, and our cost structure is very competitive, and we can deal with any situations and as needed.

Speaker #3: Got it. Thanks for taking the questions.

[Analyst] (TD Cowen): Got it. Thanks for taking the questions.

Ben Hendrix: Got it. Thanks for taking the questions.

Speaker #1: As a reminder to ask a question, press star one on your telephone keypad. Our next question comes from the line of Andrew Cooper with Raymond James.

Operator: As a reminder, to ask a question, press star 1 on your telephone keypad. Our next question comes from the line of Andrew Cooper with Raymond James. Please go ahead.

Speaker #1: Please go ahead.

Speaker #6: Hey, everybody. Thanks for the time. Maybe just one there was a comment or a couple of comments there. About some pent-up demand helping 4Q.

Andrew Cooper: Hey, everybody. Thanks for the time. Maybe just one. You know, there was a comment or a couple of comments there, about some pent-up demand helping 4Q. Can you just give a sense for the magnitude of what you feel like was sort of make up volume from maybe earlier in the year or the last few years, versus what you view as sort of that steady state, growth trajectory of the business as you think about where it sits today in the current end market?

Speaker #6: Can you just give a sense for the magnitude of what you feel like was sort of makeup volume from maybe earlier in the year or the last few years versus what you view as sort of that steady state growth trajectory of the business as you think about where it sits today in the current end market?

Speaker #4: Yeah, that's a hard one to estimate. I think if you look at our total academic and government revenues, which are publicly disclosed, starting with fourth quarter of last year, we were 21 million.

Bill McCombe: Yeah. That's a hard one to estimate. You know, I think if you look at our total academic and government revenues, which are publicly disclosed, starting with Q4 of last year, we were $21 million, then $17 million, $22 million, $18 million, and then $28 million in Q4. You know, we had a significant jump there. As I said, a lot of that is attributable to a better environment. You know, it's also possible that some of those weaker numbers in early 2025 were in fact just deferments of money that got spent later in the year. It's really impossible to sort of pause it out. You'd have to do a customer by customer survey and dive into what their intentions were, and obviously we don't do that.

Speaker #4: Then '17, '22, '18, and then '28 in Q4. So we had a significant jump there. As I said, a lot of that is attributable to a better environment.

Speaker #4: But it's also possible that some of those weaker numbers in early 2025 were, in fact, just deferments of money that got spent later in the year.

Speaker #5: It's really possible to sort of posit out. You'd have to do a customer-by-customer survey and dive into what their intentions were and obviously, we don't do that.

Andrew Cooper: Okay, maybe just thinking about...

Speaker #6: Okay. Maybe just thinking about.

Bill McCombe: I think pharma segment is much more stable and, you know, there we had pretty stable revenue between Q3 and Q4, was basically the same.

Speaker #4: I think pharma segment is much more stable and there we had pretty stable revenue in Q3 and Q4. It was basically the same.

Andrew Cooper: Sure. Helpful. Maybe just thinking about the guide a little bit and trying to put it in context of some of that commentary. You just did sort of 5-ish% organic. You talk about the market feeling like it's getting a little bit better, a little bit more stable, and you guided to 2 to 5% growth for the year. What happens in the end market to make you feel like 2% is the right number as opposed to 5? What happens to get you know, above that if we're already assuming that things are maybe a little bit better through most of 2026 than they were through most of 2025?

Speaker #3: Sure. Helpful. Maybe just thinking about the guide a little bit and trying to put it in context of some of that commentary. You just did sort of five-ish percent organic you talk about the market feeling like it's getting a little bit better, a little bit more stable.

Speaker #3: And you guided to two to five percent growth for the year. So what happens in the end market to make you feel like 2% is the right number as opposed to 5?

Speaker #3: And what happens to get you above that if we're already assuming that things are maybe a little bit better through most of '26 than they were through most of '25?

Speaker #4: Yeah, so the way we thought about the guide was we expect continuation of strong growth in service and reagents. In service, because our install base is growing.

Bill McCombe: The way we thought about the guide was, we expect continuation of strong growth in service and reagents. In service because our installed base is growing and reagents, you know, we're starting from a small base and growing quickly. We expected flat to modest growth in instruments. You know, frankly, we put in some range of contingencies to account for uncertainties because, you know, at this time last year there was some black swans that emerged, and we wanted to have a cushion to account for those sorts of things. That was the thinking that went into the range. You know, at the high end of the range, obviously, that would represent a smaller level of contingency, and, you know, better performance in the instrument business.

Speaker #4: In reagents, we're starting from a small base and growing quickly. We expected modest flat to modest growth in instruments. And then frankly, we put in some range of contingencies to account for uncertainties because at this time last year, there were some black swans that emerged and so we wanted to have a cushion to account for those sorts of things.

Speaker #4: So that was the thinking that went into the range. At the high end of the range, obviously, that would represent smaller level of contingency.

Speaker #4: And better performance in the instrument business.

Speaker #6: Okay. I'll stop there. Thank you.

Andrew Cooper: Okay. I'll stop there. Thank you.

Speaker #1: And with no further questions, this does conclude our conference call for today. You may now disconnect.

Operator: With no further questions in queue, this does conclude our conference call for today. You may now disconnect.

Bill McCombe: Thank you.

Q4 2025 Cytek BioSciences Inc Earnings Call

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